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Holarrhena antidysenterica
Holarrhena antidysenterica
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Code: HA

+ Origin: Vietnam;
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English names:  Conessi bark, kurchi bark, bitter oleander, dysentery rose-bay, Tellicherry bark.

Description:  A tree reaching about 10 m. in height or more. Bark pale-brown, lenticellate. Young twigs tomentose. Leaves opposite, oval, subsessile. Flowers white in axillary or terminal corymbiferous cyme. Follicles cylindrical in pairs, long, narrow, incurved. Seeds numerous, brownish, crowned with a tuft of long hairs at one end. All parts of the plant yield a milky juice.

Flowering period:  April - May.

Distribution:  Grows wild in the mountains and the midlands.

Parts used:  The bark, collected in February and March. Removed from the stem, the bark is well washed, then dried in the sun or in ovens.

Chemical composition:  The trunk bark contains alkaloids: conessine, nor-conessine, conessimine, isoconessimine, kurchine, conimine, conamine, conkurchine, holarrhine, holarrhenine and holarrhimine; gum, resins, tannin, triterpene alcohol, lupeol, b-sitosterol.

Therapeutic uses:  The trunk bark possesses amoebicidal properties. It is effective against amoebiasis in a daily dose of 8 to 10 g of dried trunk bark, or 4 to 6 g of dried seeds in the form of powder, tincture or liquid extract The sum of the alkaloids and conessine are also used. A bath containing a decoction of bark or leaves cures scabies. An alcoholic maceration of pounded roots is also used topically against scabies.